醋酸纤维-(S)-萘普生分子印迹复合膜的制备及分离性能

来源期刊：中南大学学报(自然科学版)2006年第6期

论文作者：钟世安 张春静 华怀杰 贺国文

文章页码：1122 - 1126

关键词：醋酸纤维膜;萘普生;酮洛芬;分子印迹复合膜;制备;分离

Key words：cellulose acetate membrane; naproxen; ketoproxen; molecularly imprinted composite membrane; preparation; separation

摘    要：以多孔醋酸纤维膜为支撑体制备醋酸纤维-(S)-萘普生分子印迹复合膜;研究萘普生模板分子与丙烯酰胺单体摩尔比及成膜溶剂种类等对分子印迹复合膜的膜通量、膜选择结合性以及膜分离选择性等的影响。研究结果表明:当萘普生模板分子与丙烯酰胺单体的摩尔比为1/10时,以四氢呋喃为成膜溶剂,在光引发条件下制得的醋酸纤维-(S)-萘普生分子印迹复合膜对萘普生和酮洛芬具有较好的分离性能;在25℃时,醋酸纤维-(S)-萘普生分子印迹复合膜的膜通量达19.7 L/(m²·h),萘普生/酮洛芬的结合选择性因子α₁为2.8,萘普生/酮洛芬的分离选择性因子α₂为5.6。

Abstract: Cellulose acetate-(S)-naproxen molecularly imprinted composite membrane was prepared by using porous cellulose acetate membrane as support, and the effects of molar ratio of the naproxen template to acrylamide monomer and kinds of solvent for membrane on the flux and selectivity of membrane were investigated.It is found that the cellulose acetate-(S)-naproxen molecularly imprinted composite membrane prepared under UV illumination has high efficiency for the separation of naproxen and ketoprofen when molar ration of the naproxen template to acrylamide monomer is 1/10 and the solvent for membrane is tetrahydrofuran. At 25℃, the flux of membrane reaches 19.7 L/(m²·h), the selective binding factor (α₁) is 2.8 and the selective separation factor (α₂) of naproxen/ketoprofen is 5.6.