简介概要

Poly(N-isopropylacrylamide)-based Vertically Sandwich-typed Hydrogel with Fast Temperature-response Speed and Its Controlled-release Characteristics

来源期刊:Journal Of Wuhan University Of Technology Materials Science Edition2012年第2期

论文作者:卢程 肖新才

文章页码:280 - 284

摘    要:A novel poly(N-isopropylacrylamide)-based sandwich-typed hydrogel,which was featured with both ends of linear poly(N-isopropylacrylamide)(PNIPAM)chains being grafted onto cross-linked PNIPAM chains,was successfully prepared in a three-step process by a method of sequential synthesis.The proposed hydrogel displays faster and hydration/dehydration dynamic response to temperature cycling owing to linear PNIPAM chains to form big-pore structure.This work may lead to high attraction for targeting drug delivery systems,polymeric pump,sensors and so on.

详情信息展示

Poly(N-isopropylacrylamide)-based Vertically Sandwich-typed Hydrogel with Fast Temperature-response Speed and Its Controlled-release Characteristics

卢程1,肖新才2

1. School of Hospital,Wuhan Institute of Technology2. School of Pharmacy,South-Central University for Nationalities

摘 要:A novel poly(N-isopropylacrylamide)-based sandwich-typed hydrogel,which was featured with both ends of linear poly(N-isopropylacrylamide)(PNIPAM)chains being grafted onto cross-linked PNIPAM chains,was successfully prepared in a three-step process by a method of sequential synthesis.The proposed hydrogel displays faster and hydration/dehydration dynamic response to temperature cycling owing to linear PNIPAM chains to form big-pore structure.This work may lead to high attraction for targeting drug delivery systems,polymeric pump,sensors and so on.

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