Effects of Rare Earth Ce on Nonspecific Immunity in Mice
来源期刊：JOURNAL OF RARE EARTHS2007年增刊第1期
论文作者：Zhang Jingjing Wang Chunguang Zhu Dongbin Wang Xiaodan Zhang Tie
Key words：Ce(NO3)3; mice; peripheral white blood cell(PWBC); clearance rate; thymus index and spleen index; rare earths;
Abstract: Mice were watered with cerous nitrate solution (2,20,200mg·kg-1) according to daily drinking water volume for 50 days and the effects of cerous nitrate on nonspecific immunity in mice were investigated. The results showed that the total number of peripheral white blood cell, the clearance rate of charcoal particles, the indices of thymus and spleen were increased on different degrees, and associated with the watering dose, noting that these indices were increased significantly by cerous nitrate at a dose of 20mg·kg-1 compared with control group. Therefore, it was concluded that the nonspecific immunity could be improved by rare earth Ce in mice.
Zhang Jingjing1，Wang Chunguang2，Zhu Dongbin3，Wang Xiaodan2，Zhang Tie2
(1.Handan Municipal Animal Husbandry and Aquatic Products Bureau, Handan 056000, China;
2.College of Traditional Chinese Veterinary Medicine, Agricultural University of Hebei, Dingzhou 073000, China;
3.School of Mechanical Engineering, Hebei University of Technology, Tianjin 300130, China)
Abstract:Mice were watered with cerous nitrate solution (2,20,200mg·kg-1) according to daily drinking water volume for 50 days and the effects of cerous nitrate on nonspecific immunity in mice were investigated. The results showed that the total number of peripheral white blood cell, the clearance rate of charcoal particles, the indices of thymus and spleen were increased on different degrees, and associated with the watering dose, noting that these indices were increased significantly by cerous nitrate at a dose of 20mg·kg-1 compared with control group. Therefore, it was concluded that the nonspecific immunity could be improved by rare earth Ce in mice.
Key words:Ce(NO3)3; mice; peripheral white blood cell(PWBC); clearance rate; thymus index and spleen index; rare earths;
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