Pilot biomechanical design of biomaterials for artificial nucleus prosthesis using 3D finite-element modeling

Qijin Huang, Guoquan Liu, Yong Li, Jin Gao, Zhengqiu Gu, Yuanzheng Ma, and Haibin Xue Materials Science and Engineering School, University of Science and Technology Beijing, Beijing 100083, China Department of Orthopaedic Surgery, PLA 309 Hospital, Beijing 100091, China

摘 要：<正>Pilot biomechanical design of biomaterials for artificial nucleus prosthesis was carried out based on the 3D finite-element method. Two 3D models of lumbar intervertebral disc respectively with a real human nucleus and with the nucleus removed were developed and validated using published experimental and clinical data. Then the models with a stainless steel nucleus prosthesis implanted and with polymer nucleus prostheses of various properties implanted were used for the 3D finite-element biomechanical analysis. All the above simulation and analysis were carried out for the L4/L5 disc under a human worst-daily compression load of 2000 N. The results show that the polymer materials with Young’s modulus of elasticity E = 0.1-100 MPa and Poisson’s ratio v= 0.35-0.5 are suitable to produce artificial nucleus prosthesis in view of biomechanical consideration.

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