Preliminary study of microstructure, mechanical properties and corrosion resistance of antibacterial Ti-15Zr-xCu alloy for dental application
来源期刊：JOURNAL OF MATERIALS SCIENCE TECHNOLOG2020年第15期
论文作者：Sharafadeen Kunle Kolawole Wang Hai Shuyuan Zhang Ziqing Sun Muhammad Ali Siddiqui Ihsan Ullah Wei Song Ke Yang
文章页码：31 - 43
摘 要：Ti-15 Zr-xCu（3≤x≤7,wt.%） novel antibacterial and antibiofilm alloys with competitive mechanical properties,biological responses and corrosion resistance were designed and fabricated.Annealing heat treatment on Ti-15 Zr-7 Cu（TZC-7 A）,after holding for 2 h at slightly above their beta transus temperature（BTT） ensured their tensile strength（UTS）,yield strength（YS） and hardness（HRV） were improved by31.2%,20% and 12.3% respectively compared to the control without Cu,Ti-15 Zr（T-15 ZA）.Although the3 wt.% Cu alloy displayed the highest elongation（26%）,the TZC-7 A alloy also possessed a good ductility.Presence of evenly dispersed Ti2 Cu and Zr2 Cu Cu-rich intermetallic phases formed as interwoven and alternating lamellae within the α+β matrix as a result of Cu addition,as revealed by X-ray diffraction（XRD）,scanning electron microscopy（SEM） and transmission electron microscopy（TEM）.These greatly contributed to their strengthening and bactericidal properties.Over 98% antibacterial effect against E.coli and S.aureus have been imparted,coupled with excellent biofilm inhibition.Potentiodynamic polarization curves showed that the TZC-7 A alloy possessed higher corrosion resistance than commercially pure titanium,cp-Ti;contact angle test revealed enhanced hydrophilicity;while confocal laser scanning microscopy（CLSM） and cell counting kit（CCK-8） assays also displayed drastically lowered bacterial adhesion rate with comparatively no cytotoxicity.Cell attachment on all alloys was similar but the best spread was obtained on TZC-7 A after 24 h.The developed alloy has good potential as an antibacterial implant material with combination of optimized properties.
Sharafadeen Kunle Kolawole1,2,3，Wang Hai2，Shuyuan Zhang2，Ziqing Sun2，Muhammad Ali Siddiqui1,2，Ihsan Ullah1,2，Wei Song2，Ke Yang2
1. School of Materials Science and Engineering, University of Science and Technology of China2. Institute of Metal Research, Chinese Academy of Sciences
摘 要：Ti-15 Zr-xCu（3≤x≤7,wt.%） novel antibacterial and antibiofilm alloys with competitive mechanical properties,biological responses and corrosion resistance were designed and fabricated.Annealing heat treatment on Ti-15 Zr-7 Cu（TZC-7 A）,after holding for 2 h at slightly above their beta transus temperature（BTT） ensured their tensile strength（UTS）,yield strength（YS） and hardness（HRV） were improved by31.2%,20% and 12.3% respectively compared to the control without Cu,Ti-15 Zr（T-15 ZA）.Although the3 wt.% Cu alloy displayed the highest elongation（26%）,the TZC-7 A alloy also possessed a good ductility.Presence of evenly dispersed Ti2 Cu and Zr2 Cu Cu-rich intermetallic phases formed as interwoven and alternating lamellae within the α+β matrix as a result of Cu addition,as revealed by X-ray diffraction（XRD）,scanning electron microscopy（SEM） and transmission electron microscopy（TEM）.These greatly contributed to their strengthening and bactericidal properties.Over 98% antibacterial effect against E.coli and S.aureus have been imparted,coupled with excellent biofilm inhibition.Potentiodynamic polarization curves showed that the TZC-7 A alloy possessed higher corrosion resistance than commercially pure titanium,cp-Ti;contact angle test revealed enhanced hydrophilicity;while confocal laser scanning microscopy（CLSM） and cell counting kit（CCK-8） assays also displayed drastically lowered bacterial adhesion rate with comparatively no cytotoxicity.Cell attachment on all alloys was similar but the best spread was obtained on TZC-7 A after 24 h.The developed alloy has good potential as an antibacterial implant material with combination of optimized properties.
关键词：
