Synthesis of NaYF4:Nd@NaLuF4@SiO2@PS colloids for fluorescence imaging in the second biological window
来源期刊：Journal of Rare Earths2018年第2期
论文作者：Dongpeng Yang Cong Cao Wei Feng Chunhui Huang Fuyou Li
文章页码：113 - 118
摘 要：Nd doped nanoparticles is commonly used as bioimaging agents but presents poor stability. Here, a polymer coating is applied to NaYF4:Nd nanoparticles using a versatile step-by-step coating strategy. The as-synthesized NaYF4:Nd@NaLuF4@SiO2@PS colloids show good stability in various polar solvent and are very stable in water at least for 6 months. These NaYF4:Nd@NaLuF4@SiO2@PS colloids can exhibit strong down converting photoluminescence when excited by 808 nm lasers. Moreover, these NaYF4:Nd@NaLuF4@SiO2@PS colloids accumulate in liver of mice when used as bio-imaging agents. which exhibit strong fluorescence luminescence in NIR Ⅱ window.
Dongpeng Yang，Cong Cao，Wei Feng，Chunhui Huang，Fuyou Li
Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers,Institutes of Biomedical Sciences & Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University
摘 要：Nd doped nanoparticles is commonly used as bioimaging agents but presents poor stability. Here, a polymer coating is applied to NaYF4:Nd nanoparticles using a versatile step-by-step coating strategy. The as-synthesized NaYF4:Nd@NaLuF4@SiO2@PS colloids show good stability in various polar solvent and are very stable in water at least for 6 months. These NaYF4:Nd@NaLuF4@SiO2@PS colloids can exhibit strong down converting photoluminescence when excited by 808 nm lasers. Moreover, these NaYF4:Nd@NaLuF4@SiO2@PS colloids accumulate in liver of mice when used as bio-imaging agents. which exhibit strong fluorescence luminescence in NIR Ⅱ window.
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