Preliminary Biocompatibility Evaluation of Regenerated Antheraea yamamai Silk Fibroin in vitro
来源期刊：Journal Of Wuhan University Of Technology Materials Science Edition2011年第6期
论文作者：王建南
文章页码：1044 - 1048
摘 要：The study aimed to investigate the adhesion, morphology and proliferation of Sprague Dawley （SD） albino rat bone marrow-derived mesenchymal stem cells （BMSCs） by inverted microscope, cell counting, MTT test and laser scanning confocal microscop （LSCM）. On the regenerated A yamamai SF film or blend films, the cell morphology was almost the same as that on collagen （collagen type I） film, the cell adhesion rate was higher than that on plastic cell plate and B mori SF film after 1 h （p < 0.01） of culture, and the cell proliferation was significantly higher than that on collagen film （p < 0.01） and plastic cell plate （p < 0.01）, and also obviously better than that on B mori SF film. On the other hand, the viability of BMSCs in the regenerated A yamamai SF porous scaffold was better than that in B mori SF porous scaffold and medical grade polyvinyl alcohol （PVA） sponge.
王建南
National Engineering Laboratory for Modern Silk,College of Textile and Clothing Engineering,Soochow University
摘 要：The study aimed to investigate the adhesion, morphology and proliferation of Sprague Dawley （SD） albino rat bone marrow-derived mesenchymal stem cells （BMSCs） by inverted microscope, cell counting, MTT test and laser scanning confocal microscop （LSCM）. On the regenerated A yamamai SF film or blend films, the cell morphology was almost the same as that on collagen （collagen type I） film, the cell adhesion rate was higher than that on plastic cell plate and B mori SF film after 1 h （p < 0.01） of culture, and the cell proliferation was significantly higher than that on collagen film （p < 0.01） and plastic cell plate （p < 0.01）, and also obviously better than that on B mori SF film. On the other hand, the viability of BMSCs in the regenerated A yamamai SF porous scaffold was better than that in B mori SF porous scaffold and medical grade polyvinyl alcohol （PVA） sponge.
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