Role of Cu element in biomedical metal alloy design
来源期刊：Rare Metals2019年第6期
论文作者：Er-Lin Zhang Shan Fu Ruo-Xian Wang Hai-Xia Li Ying Liu Zhi-Qiang Ma Guang-Kun Liu Chen-Shun Zhu Gao-Wu Qin Da-Fu Chen
文章页码：476 - 494
摘 要：Biomedical metals are widely used as implant materials in the human or animal body to repair organs and restore function, such as heart valves, meninges, peritoneum and artificial organs.Alloying element affects the microstructure, mechanical property, corrosion resistance and wear resistance, but also influences the antibacterial and biological activity.Recently, antibacterial metal alloys have shown great potential as a new kind of biomedical materials, in which Cu has been widely used as antibacterial agent element.In addition, biodegradable metal alloys, including magnesium alloy and zinc alloy, also have attracted much attention worldwide.Cu was also used as alloying element to adjust the degradation rate.Thus, the role of Cu in the alloy design will be very important for the development of new alloy.In this paper, we summarized the recent research results on the Cu-containing metal alloy for biomedical application and hoped that this review would give more suggestions for the further development of biomedical metal alloy.
Er-Lin Zhang1，Shan Fu1，Ruo-Xian Wang1，Hai-Xia Li1，Ying Liu1，Zhi-Qiang Ma1，Guang-Kun Liu1，Chen-Shun Zhu1，Gao-Wu Qin1，Da-Fu Chen2
1. School of Materials Science and Engineering, Key Laboratory for Anisotropy and Texture of Materials, Education Ministry of China, Northeastern University2. Laboratory of Bone Tissue Engineering, Beijing Laboratory of Biomedical Materials, Beijing Research Institute of Orthopaedics and Traumatology, Beijing Jishuitan Hospital
摘 要：Biomedical metals are widely used as implant materials in the human or animal body to repair organs and restore function, such as heart valves, meninges, peritoneum and artificial organs.Alloying element affects the microstructure, mechanical property, corrosion resistance and wear resistance, but also influences the antibacterial and biological activity.Recently, antibacterial metal alloys have shown great potential as a new kind of biomedical materials, in which Cu has been widely used as antibacterial agent element.In addition, biodegradable metal alloys, including magnesium alloy and zinc alloy, also have attracted much attention worldwide.Cu was also used as alloying element to adjust the degradation rate.Thus, the role of Cu in the alloy design will be very important for the development of new alloy.In this paper, we summarized the recent research results on the Cu-containing metal alloy for biomedical application and hoped that this review would give more suggestions for the further development of biomedical metal alloy.
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