Preparation and Characterization of Carboxyl Functionalized Fluorescent Mesoporous Silica Nanoparticles Containing 8-Hydroxyquinolinate Zinc Complexes
来源期刊：Journal Of Wuhan University Of Technology Materials Science Edition2019年第4期
论文作者：王晚霞 WANG Youyun WANG Yu ZHU Hongda SUN Honghao 刘明星
文章页码：973 - 978
摘 要：Fluorescent mesoporous silica nanoparticles functionalized with carboxyl group（Znq-CMSCOOH） were successfully synthesized by in situ formation route of 8-hydroxyquinolinate zinc complexes in channels of mesoporous silica nanoparticles and post-grafting of carboxyl group on the surface. Moreover,the particle size and structural properties of Znq-CMS-COOH were characterized by transmission electron microscopy（TEM）, field emission scanning electron microscopy（FE-SEM）, dynamic light scattering（DLS）,Fourier transform infrared spectroscopy（FT-IR）, UV-vis spectrometer, fluorescence spectrometer and nitrogen adsorption-desorption measurements. The obtained results suggest that the Znq-CMS-COOH presents the uniform spherical shape with the mean diameter of about 85 nm and the obvious wormhole arrangement mesoporous. In addition, the Znq-CMS-COOH possesses green fluorescence with the emission peaks at 495 nm. So the Znq-CMS-COOH, which is beneficial to further modification and tracing, might be a great potential carrier for applying in drug delivery system in the future.
王晚霞，WANG Youyun，WANG Yu，ZHU Hongda，SUN Honghao，刘明星
Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei Provincial Cooperative Innovation Center of Industrial Fermentation, National "111" Center for Cellular Regulation and Molecular Phormaceutics, Hubei Key Laboratory of Industrial Microbiology,Hubei University of Technology
摘 要：Fluorescent mesoporous silica nanoparticles functionalized with carboxyl group（Znq-CMSCOOH） were successfully synthesized by in situ formation route of 8-hydroxyquinolinate zinc complexes in channels of mesoporous silica nanoparticles and post-grafting of carboxyl group on the surface. Moreover,the particle size and structural properties of Znq-CMS-COOH were characterized by transmission electron microscopy（TEM）, field emission scanning electron microscopy（FE-SEM）, dynamic light scattering（DLS）,Fourier transform infrared spectroscopy（FT-IR）, UV-vis spectrometer, fluorescence spectrometer and nitrogen adsorption-desorption measurements. The obtained results suggest that the Znq-CMS-COOH presents the uniform spherical shape with the mean diameter of about 85 nm and the obvious wormhole arrangement mesoporous. In addition, the Znq-CMS-COOH possesses green fluorescence with the emission peaks at 495 nm. So the Znq-CMS-COOH, which is beneficial to further modification and tracing, might be a great potential carrier for applying in drug delivery system in the future.
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