Distribution and Accumulation of Neodymium and Its Effect on Secretion of Progesterone in Mice
来源期刊：JOURNAL OF RARE EARTHS2004年第2期
论文作者：刘玉 王元兴 陈祖义
Key words：botany; neodymium; radioisotope tracer; distribution and accumulation; secretion of progesterone; rare earths;
Abstract: Distribution and accumulation of Nd,and its effect on secretion of progesterone in mice were studied using radioisotope tracer( 147Nd)technique.Following single intraperitoneal administration of neodymium traced with 147Nd at a dose of 200 mg*kg-1,uneven distribution of the radioactive Nd occurred in various tissues and organs.Much amount of 147Nd accumulates in the bone,and the residue increases with the lapse of time.Some amount of radioactivity was also detected in eyes,blood and brain,but the accumulation decreased with the time due to excretion and re-distribution in mice.In comparison with controls,concentration of progesterone is found to be significantly lower in the serum of administered mice,indicating a significantly inhibitory effect of Nd on secretion of progesterone.
刘玉1，王元兴1，陈祖义2
(1.College of Animal Science and Technology;
2.College of Science,Nanjing Agricultural University,Nanjing 210095,China)
Abstract:Distribution and accumulation of Nd,and its effect on secretion of progesterone in mice were studied using radioisotope tracer( 147Nd)technique.Following single intraperitoneal administration of neodymium traced with 147Nd at a dose of 200 mg*kg-1,uneven distribution of the radioactive Nd occurred in various tissues and organs.Much amount of 147Nd accumulates in the bone,and the residue increases with the lapse of time.Some amount of radioactivity was also detected in eyes,blood and brain,but the accumulation decreased with the time due to excretion and re-distribution in mice.In comparison with controls,concentration of progesterone is found to be significantly lower in the serum of administered mice,indicating a significantly inhibitory effect of Nd on secretion of progesterone.
Key words:botany; neodymium; radioisotope tracer; distribution and accumulation; secretion of progesterone; rare earths;
【全文内容正在添加中】
