Preparation, characterization, and antibacterial activity of γ-irradiated silver nanoparticles in aqueous gelatin

Majid Darroudi¹，Mansor B. Ahmad²，Mohammad Hakimi³，Reza Zamiri⁴，Ali Khorsand Zak⁵，Hasan Ali Hosseini³，Mohsen Zargar⁶

1. Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences2. Department of Chemistry, Faculty of Science, Universiti Putra Malaysia3. Chemistry Department, Payame Noor University4. Department of Materials Engineering and Ceramic, CICECO, University of Aveiro5. Electroceramics and Materials Lab., Physics Department, Faculty of Science, Ferdowsi University of Mashhad6. Faculty of Science, Qom Branch, Islamic Azad University

摘 要：Colloidal silver nanoparticles （Ag-NPs） were obtained through γ-irradiation of aqueous solutions containing AgNO 3 and gelatin as a silver source and stabilizer, respectively. The absorbed dose of γ-irradiation influences the particle diameter of the Ag-NPs, as evidenced from surface plasmon resonance （SPR） and transmission electron microscopy （TEM） images. When the γ-irradiation dose was increased （from 2 to 50 kGy）, the mean particle size was decreased continuously as a result of γ-induced Ag-NPs fragmentation. The antibacterial properties of the Ag-NPs were tested against Methicillinresistant Staphylococcus aureus （MRSA） （Gram-positive） and Pseudomonas aeruginosa （P.a） （Gram-negative） bacteria. This approach reveals that the γ-irradiation-mediated method is a promising simple route for synthesizing highly stable Ag-NPs in aqueous solutions with good antibacterial properties for different applications.

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