Physically Cross-linked Hydrogels with Excellent Self-healing, Moldability, Antibacterial Activities and Adjustable Mechanical Properties
来源期刊：Journal Of Wuhan University Of Technology Materials Science Edition2019年第6期
论文作者：何广华 CAO Jilong WANG Cheng FAN Lihong YIN Yihua CAI Weiquan 陶圣祥
文章页码：1484 - 1494
摘 要：A simple strategy was developed to prepare a tough, self-healing, antibacterial and moldable hydrogel by introducing the natural polyphenolic compound tannic acid（TA） as a cross-linking center for hydrogen bonds. Polyvinyl alcohol（PVA）-TA hydrogel was prepared by physical mixing using PVA as a main component and TA as a cross-linker. There were two types of physical cross linking bonds in the PVA-TA hydrogel network, which were weaker hydrogen bonds between PVA molecular chains and stronger hydrogen bonds between PVA and TA molecules. The mechanical properties and self-healing ability could be adjusted by changing the contents of PVA and TA. The hydrogel possessed not only high mechanical strength（305 kPa tensile strength and 864 kPa compressive strength）, moldability and excellent self-healing properties（95% selfhealing efficiency） but also good antibacterial abilities against S. aureus and E. coli. In addition, after soaking the dried hydrogel in 90 ℃ deionized water for 4 h, they could also regain their self-healing ability to a certain extent. The hydrogels have potential applications in the biomedical fields.
何广华1，CAO Jilong1，WANG Cheng1，FAN Lihong1，YIN Yihua1，CAI Weiquan1，陶圣祥2
1. School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology2. Department of Orthopedics, Zhongnan Hospital of Wuhan University
摘 要：A simple strategy was developed to prepare a tough, self-healing, antibacterial and moldable hydrogel by introducing the natural polyphenolic compound tannic acid（TA） as a cross-linking center for hydrogen bonds. Polyvinyl alcohol（PVA）-TA hydrogel was prepared by physical mixing using PVA as a main component and TA as a cross-linker. There were two types of physical cross linking bonds in the PVA-TA hydrogel network, which were weaker hydrogen bonds between PVA molecular chains and stronger hydrogen bonds between PVA and TA molecules. The mechanical properties and self-healing ability could be adjusted by changing the contents of PVA and TA. The hydrogel possessed not only high mechanical strength（305 kPa tensile strength and 864 kPa compressive strength）, moldability and excellent self-healing properties（95% selfhealing efficiency） but also good antibacterial abilities against S. aureus and E. coli. In addition, after soaking the dried hydrogel in 90 ℃ deionized water for 4 h, they could also regain their self-healing ability to a certain extent. The hydrogels have potential applications in the biomedical fields.
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