Synthesis of PEI-Functionalized Magnetic Nanoparticles for Capturing Bacteria
来源期刊：Journal Of Wuhan University Of Technology Materials Science Edition2019年第1期
论文作者：陈保利 谢浩 ZHANG Ao LIU Nian LI Qichang GUO Junhui SU Baolian
文章页码：236 - 242
摘 要：Polyethyleneimine（PEI） functionalized Fe3O4 MNPs were synthesized by a modified hypothermal oxidative hydrolysis method. The magnetic nanoparticles showed positively charged surface, strong magnetic responsivity and uniform particle size distribution at 56.1±0.6 nm. Aggregation of these magnetic nanoparticles were observed on the surface of different type of bacteria. Magnetic capturing of bacteria were facilitated by these magnetic nanoparticles. The capturing efficiency could reach 90% after two rounds of interactions of 5 minutes. The mechanism and process of interactions between bacteria and polyethyleneimine functionalized Fe3O4 magnetic nanoparticles were explored and discussed. The present study not only provides insight into interactions between Fe3O4@PEI MNPs and bacterial cells, but also opens a new avenue for designing and applying Fe3O4@PEI MNPs as biosensors in microbiology, medicine, and environmental science.
陈保利1，谢浩1，ZHANG Ao1，LIU Nian1，LI Qichang1，GUO Junhui1，SU Baolian2,3
1. School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology2. State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology3. Laboratory of Inorganic Materials Chemistry, University of Namur
摘 要：Polyethyleneimine（PEI） functionalized Fe3O4 MNPs were synthesized by a modified hypothermal oxidative hydrolysis method. The magnetic nanoparticles showed positively charged surface, strong magnetic responsivity and uniform particle size distribution at 56.1±0.6 nm. Aggregation of these magnetic nanoparticles were observed on the surface of different type of bacteria. Magnetic capturing of bacteria were facilitated by these magnetic nanoparticles. The capturing efficiency could reach 90% after two rounds of interactions of 5 minutes. The mechanism and process of interactions between bacteria and polyethyleneimine functionalized Fe3O4 magnetic nanoparticles were explored and discussed. The present study not only provides insight into interactions between Fe3O4@PEI MNPs and bacterial cells, but also opens a new avenue for designing and applying Fe3O4@PEI MNPs as biosensors in microbiology, medicine, and environmental science.
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