Dual-functionalization based on combination of quercetin compound and rare earth nanoparticle
来源期刊：Journal of Rare Earths2013年第7期
论文作者：王坤杰 吴平 李红霞 李明亮 张德懿 冯辉霞
文章页码：709 - 714
摘 要：While the nanoparticles like La2O3 and other rare earth oxides were believed to be able to provide effective scavenging hydroxyl radical.Quercetin,a hydrophobic agent,showed some potential antibacterial activity.The present work successfully performed the surface modification of rare earth nanoparticle using facile and general strategy.In specific,the hydrophobic quercetin was grafted on the rare earth nanoparticle through the coupling with silane.The surface modified nanoparticle was characterized by Fourier-transform infrared（FTIR）,thermogravimetric analysis（TGA）,and scanning electron microscopy（SEM）.The surface modification helped to retain both the scavenging hydroxyl radical property of rare earth nanoparticle and the antibacterial activity of quercetin.This dual-function properties showed potential for application in the development of biomedicine such as antioxidant,anti-inflammatory,antibacterial and anticancer.
王坤杰1，吴平1，李红霞1，李明亮1，张德懿1，冯辉霞1
1. College of Petrochemical Technology,Lanzhou University of Technology
摘 要：While the nanoparticles like La2O3 and other rare earth oxides were believed to be able to provide effective scavenging hydroxyl radical.Quercetin,a hydrophobic agent,showed some potential antibacterial activity.The present work successfully performed the surface modification of rare earth nanoparticle using facile and general strategy.In specific,the hydrophobic quercetin was grafted on the rare earth nanoparticle through the coupling with silane.The surface modified nanoparticle was characterized by Fourier-transform infrared（FTIR）,thermogravimetric analysis（TGA）,and scanning electron microscopy（SEM）.The surface modification helped to retain both the scavenging hydroxyl radical property of rare earth nanoparticle and the antibacterial activity of quercetin.This dual-function properties showed potential for application in the development of biomedicine such as antioxidant,anti-inflammatory,antibacterial and anticancer.
关键词：
