Performance enhancement of paper-based SERS chips by shell-isolated nanoparticle-enhanced Raman spectroscopy
来源期刊：JOURNAL OF MATERIALS SCIENCE TECHNOLOG2019年第10期
论文作者：Mingze Sun Binghan Li Xiaojia Liu Jiayin Chen Taotao Mu Lianqing Zhu Jinhong Guo Xing Ma
文章页码：2207 - 2212
摘 要：Paper-based flexible surface-enhanced Raman scattering（SERS） chips have been demonstrated to have great potential for future practical applications in point-of-care testing（POCT） due to the potentials of massive fabrication, low cost, efficient sample collection and short signal acquisition time. In this work,common filter paper and Ag@Si O2 core-shell nanoparticles（NP） have been utilized to fabricate SERS chips based on shell-isolated nanoparticle-enhanced Raman spectroscopy（SHINERS）. The SERS performance of the chips for POCT applications was systematically investigated. We used crystal violet as the model molecule to study the influence of the size of the Ag core and the thickness of the Si O2 coating layer on the SERS activity and then the morphology optimized Ag@Si O2 core-shell NPs was employed to detect thiram. By utilizing the smartphone as a miniaturized Raman spectral analyzer, high SERS sensitivity of thiram with a detection limit of 10-9 M was obtained. The study on the stability of the SERS chips shows that a Si O2 shell of 3 nm can effectively protect the as-prepared SERS chips against oxidation in ambient atmosphere without seriously weakening the SERS sensitivity. Our results indicated that the SERS chips by SHINERS had great potential of practical application, such as pesticide residues detection in POCT.
Mingze Sun1,2，Binghan Li3,2，Xiaojia Liu3,2，Jiayin Chen3,2，Taotao Mu4，Lianqing Zhu4，Jinhong Guo5，Xing Ma3,2
1. State Key Laboratory of Advanced Welding and Joining, Harbin Institute of ((Technology Shenzhen))2. Flexible Printed Electronics Technology Center, Harbin Institute of (Technology Shenzhen)3. State Key Laboratory of Advanced Welding and Joining, Harbin Institute of (Technology Shenzhen)4. Beijing Engineering Research Center of Optoelectronic Information and Instruments, Beijing Information Science and Technology University5. School of Information and Communication Engineering, University of Electronic Science and Technology of China
摘 要：Paper-based flexible surface-enhanced Raman scattering（SERS） chips have been demonstrated to have great potential for future practical applications in point-of-care testing（POCT） due to the potentials of massive fabrication, low cost, efficient sample collection and short signal acquisition time. In this work,common filter paper and Ag@Si O2 core-shell nanoparticles（NP） have been utilized to fabricate SERS chips based on shell-isolated nanoparticle-enhanced Raman spectroscopy（SHINERS）. The SERS performance of the chips for POCT applications was systematically investigated. We used crystal violet as the model molecule to study the influence of the size of the Ag core and the thickness of the Si O2 coating layer on the SERS activity and then the morphology optimized Ag@Si O2 core-shell NPs was employed to detect thiram. By utilizing the smartphone as a miniaturized Raman spectral analyzer, high SERS sensitivity of thiram with a detection limit of 10-9 M was obtained. The study on the stability of the SERS chips shows that a Si O2 shell of 3 nm can effectively protect the as-prepared SERS chips against oxidation in ambient atmosphere without seriously weakening the SERS sensitivity. Our results indicated that the SERS chips by SHINERS had great potential of practical application, such as pesticide residues detection in POCT.
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