Gd3+ doped CuInS2/ZnS nanocrystals with high quantum yield for bimodal fluorescence/magnetic resonance imaging
来源期刊：JOURNAL OF RARE EARTHS2017年第4期
论文作者：郁彩艳 宣曈曈 楼孙棋 刘潇潇 廉国海 李会利
文章页码：382 - 388
摘 要：Recently, CuInS2/ZnS nanocrystals（CISZ NCs） have been widely used in many fields due to their excellent properties, such as tunable photoluminescence（PL） spectra, broad absorption, and non-toxicity. In order to expand the application of CISZ NCs, Gd3+ was introduced into the host serving as paramagnetic modules to achieve magnetic resonance imaging（MRI） enhancement. MRI probes could provide high-resolution anatomical information. The derived Gd-Cu-In-S/ZnS nanocrystals（GCISZNCs） exhibited the strong orange photoluminescence with a quantum yield of 57.6% and significantly high longitudinal relaxivity（r1=20.4 mmol/s） in comparison with commercial Magnevist（Gd-DTPA, r1=4.5 mmol/s）. Effective enhancement of MRI and improved longitudinal relaxivity as well as lower cytotoxicity mode GCISZ NCs an ideal MRI probe, suggesting its potential and significance in practical biological and clinic applications in the future.
郁彩艳1，宣曈曈2，楼孙棋1，刘潇潇3，廉国海4，李会利1
1. Engineering Research Center for Nanophotonics & Advanced Instrument,Ministry of Education,School of Physics and Materials Science,East China Normal University2. Ministry of Education Key Laboratory of Bioinorganic and Synthetic Chemistry,State Key Laboratory of Optoelectronic Materials and Technologies,KLGHEI of Environment and Energy Chemistry,School of Chemistry,Sun Yat-Sen University3. Engineering Department,Hunan Electric Power Research Institute of State Grid4. Marketing Department,Hunan Electric Power Company of State Grid
摘 要：Recently, CuInS2/ZnS nanocrystals（CISZ NCs） have been widely used in many fields due to their excellent properties, such as tunable photoluminescence（PL） spectra, broad absorption, and non-toxicity. In order to expand the application of CISZ NCs, Gd3+ was introduced into the host serving as paramagnetic modules to achieve magnetic resonance imaging（MRI） enhancement. MRI probes could provide high-resolution anatomical information. The derived Gd-Cu-In-S/ZnS nanocrystals（GCISZNCs） exhibited the strong orange photoluminescence with a quantum yield of 57.6% and significantly high longitudinal relaxivity（r1=20.4 mmol/s） in comparison with commercial Magnevist（Gd-DTPA, r1=4.5 mmol/s）. Effective enhancement of MRI and improved longitudinal relaxivity as well as lower cytotoxicity mode GCISZ NCs an ideal MRI probe, suggesting its potential and significance in practical biological and clinic applications in the future.
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