Synthesis,characterization and cell imaging properties of rare earth compounds based on hydroxamate ligand
来源期刊：Journal of Rare Earths2018年第4期
论文作者：Linyan Yang Yanping Zhang Liwei Hu Yunhe Zong Ruili Zhao Tianming Jin Wen Gu
文章页码：418 - 423
摘 要：Six binuclear rare earth compounds were synthesized through the ligand of 4-Bromo-N-hydroxy-Nmethyl-benzamide（sH2 bha）. Compounds 1-3 are isomorphous, and compound 1 is crystallized in the monoclinic system with the P21/c space group. Compounds 4 and 5 are isomorphous, and compound 4 is crystallized in the triclinic system with the P-1 space group. Compound 6 is crystallized in the triclinic system with the P-1 space group. The compounds were characterized by thermogravimetric analysis（TGA） and IR spectroscopy. The fluorescence spectrum in the visible area shows characteristic peaks of Eu, Tb, and Dy compounds. The efficiency of Eu compound on the viability of PC3 cells was assessed using CCK8 assays. From the CCK8 results, ionic concentration may have a great effect on PC3 cells’ proliferation. Eu compound shows red fluorescence in the cytoplasm of PC3 cell. As for Eu compound, it might have potential application in cell imaging technology.
Linyan Yang1,2，Yanping Zhang3，Liwei Hu1，Yunhe Zong1，Ruili Zhao1，Tianming Jin1，Wen Gu3,4
1. College of Animal Science and Veterinary Medicine,Tianjin Agricultural University2. Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources,Guangxi Normal University3. College of Chemistry,Collaborative Innovation Center of Chemical Science and Engineering(Tianjin),Nankai University4. Key Laboratory of Advanced Energy Materials Chemistry (KIAEMC),Nankai University
摘 要：Six binuclear rare earth compounds were synthesized through the ligand of 4-Bromo-N-hydroxy-Nmethyl-benzamide（sH2 bha）. Compounds 1-3 are isomorphous, and compound 1 is crystallized in the monoclinic system with the P21/c space group. Compounds 4 and 5 are isomorphous, and compound 4 is crystallized in the triclinic system with the P-1 space group. Compound 6 is crystallized in the triclinic system with the P-1 space group. The compounds were characterized by thermogravimetric analysis（TGA） and IR spectroscopy. The fluorescence spectrum in the visible area shows characteristic peaks of Eu, Tb, and Dy compounds. The efficiency of Eu compound on the viability of PC3 cells was assessed using CCK8 assays. From the CCK8 results, ionic concentration may have a great effect on PC3 cells’ proliferation. Eu compound shows red fluorescence in the cytoplasm of PC3 cell. As for Eu compound, it might have potential application in cell imaging technology.
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