基于AFM的钛合金表面红细胞力学性能

谢雄¹，谭建平¹，龙东平²，刘云龙¹

(1. 中南大学 机电工程学院，湖南 长沙，410083；2. 湖南科技大学 机电工程学院，湖南 湘潭，411201)

摘 要：从微摩擦的角度研究血液的吸附机理，建立血细胞黏附力模型，利用CSPM5000型原子力显微镜(AFM)观察钛合金表面及吸附在其基底上的红细胞表面的二维和三维形貌，从材料的表面特征出发，研究不同红细胞压积HCT的血液在不同粗糙度的钛合金表面的接触角、黏附功的变化规律，以及材料表面性能对血液的润湿性、润滑性能和相容性的影响规律。结果表明：随着血液HCT的增加，血液对钛合金表面的接触角上升，润滑性能提高；随着合金表面粗糙度值的增加，其黏附功呈均匀上升，接触角下降；钛合金表面的亲水性越好，其表面血液润滑性能越好。研究结果为改进血液润滑效果、提高润滑效率、减少血细胞受损提供基础和依据。

关键词：钛合金；红细胞；力学性能；原子力显微镜(AFM)

Mechanical properties of erythrocyte on titanium alloy surface based on AFM

XIE Xiong¹, TAN Jianping¹, LONG Dongping², LIU Yunlong¹

(1. School of Mechanical and Electrical Engineering, Central South University, Changsha 410083, China;2. College of Electro mechanical Engineering, Hunan University of Science and Technology, Xiangtan 411201, China)

Abstract:According to the study on micro-friction adsorption mechanism of blood, the adhesion model of blood cells was established. By using the CSPM5000 atomic force microscope, the 2D and 3D surface topographies of erythrocyte which adsorbed in the basement of titanium alloy were observed. Based on the surface characteristics of materials, the contact angle and adhesive work of erythrocyte with different HCT on the surface of titanium with different surface roughness were studied. The results show that: with the increase of the HCT in blood, the contact angle between blood and titanium surface increases and the lubrication performance is improved; with the increase of roughness of titanium surface, the contact angle and adhesive work increase; with the increase of hydrophilicity of titanium, the lubrication performance is improved. The results provide a foundation to improve the lubricating effect and reduse the damage of erythrocyte.

Key words:titanium alloy; erythrocyte; mechanical properties; atomic force microscope (AFM)