Novel Terbium Chelate Doped Fluorescent Silica Nanoparticles
来源期刊：JOURNAL OF RARE EARTHS2006年第2期
论文作者：Meng Jianxin Liu Yingliang Man Shiqing Wang Haiming Ning Qiaoyu
Key words：terbium; microemulsion; fluorescent nanoparticles; rare earths;
Abstract: Novel terbium chelate doped silica fluorescent nanoparticles were prepared and characterized.The preparation was carried out in water-in-oil (W/O) microemulsion containing monomer precursor (pAB-DTPAA-APTEOS), Triton X-100, n-hexanol, and cyclohexane by controlling copolymerization of tetraethyl orthosilicate and 3-aminopropyl-triethyloxysilane.The nanoparticles are spherical and uniform in size, about 30 nm in diameter, strongly fluorescent, and highly stable.The amino groups directly introduced to the surface of the nanoparticles using APTEOS during preparation made the surface modification and bioconjugation of the nanoparticles easier.The nanoparticles are expected as an efficient time-resolved luminescence biological label.
Meng Jianxin1，Liu Yingliang1，Man Shiqing1，Wang Haiming1，Ning Qiaoyu1
(1.Institute of Nano-Chemistry, Department of Chemistry, Jinan University, Guangzhou 510632, China)
Abstract:Novel terbium chelate doped silica fluorescent nanoparticles were prepared and characterized.The preparation was carried out in water-in-oil (W/O) microemulsion containing monomer precursor (pAB-DTPAA-APTEOS), Triton X-100, n-hexanol, and cyclohexane by controlling copolymerization of tetraethyl orthosilicate and 3-aminopropyl-triethyloxysilane.The nanoparticles are spherical and uniform in size, about 30 nm in diameter, strongly fluorescent, and highly stable.The amino groups directly introduced to the surface of the nanoparticles using APTEOS during preparation made the surface modification and bioconjugation of the nanoparticles easier.The nanoparticles are expected as an efficient time-resolved luminescence biological label.
Key words:terbium; microemulsion; fluorescent nanoparticles; rare earths;
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