Synthesis of p-nitrophenol under normal pressure with A-1phase transfer catalysis

来源期刊：中南大学学报(英文版)2001年第1期

论文作者：ZHONG Shi-an OUYANG Xi ZHOU Chun-shan CHENG Ben-cheng

文章页码：54 - 56

Key words：phase transfer catalysis; p-nitrophenol; synthesis

Abstract: p-nitrophenol is synthesized using p-nitrochlorobenzene and sodium hydroxide with phase transfer catalyst. Several reaction factors, such as catalyst type, the amounts of catalysts and sodium hydroxide, the concentration of sodium hydroxide solution as well as reaction time, affect greatly the yield of p-nitrophenol.The optimum reaction conditions are as follows: A-1 used as phase transfer catalyst whose consumption is 6%(mole fraction) of p-nitrochlorobenzene; the molar ratio of sodium hydroxide to p-nitrochlorobenzene is 3:1;the concentration of sodium hydroxide solution is 50% (mass fraction). Nitrobenzene, whose molar amount is 2.45 times asmuch as thatof p-nitrochlorobenzene; reaction time is 7 h at140℃under normal pressure. The final yield of p-nitrophenol is 83.6%.