New nitinol endovascular stent-graft system for abdominal aortic aneurysm with finite element analysis and experimental verification
来源期刊：Rare Metals2019年第6期
论文作者：Xiao-Chen Zhou Ming Zhao Yu-Feng Zheng Zhi-Li Sun
文章页码：495 - 502
摘 要：Abdominal aortic aneurysm（AAA） is one of the most common and catastrophic manifestations of the acute aortic syndrome that can be treated with endovascular aneurysm repair（EVAR） which requires a specially designed stent-graft system.In this work, a self-expanding nickel–titanium（nitinol） stent-graft system is aiming at AAA using finite element analysis（FEA） methods to analyze both fatigue behaviors and radial forces.Based on the systematic analysis of the parametric variations, a final stent-graft system was developed by the selection and arrangement of the individual stent components, targeting an optimal performance for the treatment of AAA.Experimental tests, animal tests and clinical trials were carried out to confirm the results.Both animal trials and clinical trials showed comparable curative effects with Medtronic Endurant stent-graft（SG） systems.
Xiao-Chen Zhou1，Ming Zhao4，Yu-Feng Zheng1,5，Zhi-Li Sun5
1. Department of Materials Science and Engineering, College of Engineering, Peking University4. Schlumberger Technology Corporation5. State Key Laboratory for Turbulence and Complex System,College of Engineering, Peking University
摘 要：Abdominal aortic aneurysm（AAA） is one of the most common and catastrophic manifestations of the acute aortic syndrome that can be treated with endovascular aneurysm repair（EVAR） which requires a specially designed stent-graft system.In this work, a self-expanding nickel–titanium（nitinol） stent-graft system is aiming at AAA using finite element analysis（FEA） methods to analyze both fatigue behaviors and radial forces.Based on the systematic analysis of the parametric variations, a final stent-graft system was developed by the selection and arrangement of the individual stent components, targeting an optimal performance for the treatment of AAA.Experimental tests, animal tests and clinical trials were carried out to confirm the results.Both animal trials and clinical trials showed comparable curative effects with Medtronic Endurant stent-graft（SG） systems.
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