Changes of Calpain mRNA Level in Rat Hepatocyte after Recurrent Intraperitoneal Administration of Ceium Nitrate
来源期刊:JOURNAL OF RARE EARTHS2001年第2期
论文作者:王艇 杨维东 雷衡毅 杨燕生 龚孟濂 刘洁生
Abstract: The effect of Ce(NO3)3 on expression of calpain in rat hepatocyte was studied by means of reverse transcription-polymerase chain reaction (RT-PCR). The result shows that high dose of Ce(NO3)3 (50 mg.kg-1) induces the increase of expression of calpain mRNA, but low dose of Ce(NO3)3 (1 mg.kg-1) does not. Possible mechanism for this phenomenon was discussed.
王艇1,杨维东2,雷衡毅3,杨燕生3,龚孟濂3,刘洁生2
(1.School of Life Sciences, Zhongshan University,;
2.Department of Biotechnology, Jinan University,;
3.School of Chemistry and Chemical Engineering, Zhongshan University,)
Abstract:The effect of Ce(NO3)3 on expression of calpain in rat hepatocyte was studied by means of reverse transcription-polymerase chain reaction (RT-PCR). The result shows that high dose of Ce(NO3)3 (50 mg.kg-1) induces the increase of expression of calpain mRNA, but low dose of Ce(NO3)3 (1 mg.kg-1) does not. Possible mechanism for this phenomenon was discussed.
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