Preparation and Characterization of the System SiO2-CaO-P2O5 Bioactive Glasses by Microemulsion Approach
来源期刊：Journal Of Wuhan University Of Technology Materials Science Edition2013年第5期
论文作者：王洪新 CHEN Xiaoming WANG Youfa CHENG Dongji
文章页码：1053 - 1057
摘 要：The system of SiO2-CaO-P2O5 bioactive glasses（BG） were successfully synthesized by microemulsion approach.X-ray diffraction（XRD）,scanning electron micro scopy（SEM） and energy dispersive X-ray（EDX） analyses,transmission electron microscopy（TEM）,Fourier transform infrared spectroscopy（FTIR）,BET N2 gas adsorption analysis techniques were utilized in order to evaluate the phase composition,dimension,morphology,interconnectivity of pores and particle size of the synthesized BG respectiveely.The biocompatibility of BG was assessed by using dimethylthiazol diphenyl tetrazolium bromide（MTT）.The BG scaffolds were implanted in rabbit mandibles and studied histologically.The results showed that the BG with a particle size less than 100 nm was prepared successfully.The measured BET specific surface area and pore volume was 113.9 m2/g and 0.28 cm3/g respectively.Cell cultures revealed that BG has been shown to have good biocompatibility and is also beneficial to the survival of Schwann cells,which can promote cell proliferation in vivo assay indicating that the BG can promote osteoconductivity.
王洪新1，CHEN Xiaoming1，WANG Youfa1，CHENG Dongji2
1. Biomedical Materials and Engineering Research Center,Wuhan University of Technology2. Department of Mechanical and Electronic Engineering,West Anhui University
摘 要：The system of SiO2-CaO-P2O5 bioactive glasses（BG） were successfully synthesized by microemulsion approach.X-ray diffraction（XRD）,scanning electron micro scopy（SEM） and energy dispersive X-ray（EDX） analyses,transmission electron microscopy（TEM）,Fourier transform infrared spectroscopy（FTIR）,BET N2 gas adsorption analysis techniques were utilized in order to evaluate the phase composition,dimension,morphology,interconnectivity of pores and particle size of the synthesized BG respectiveely.The biocompatibility of BG was assessed by using dimethylthiazol diphenyl tetrazolium bromide（MTT）.The BG scaffolds were implanted in rabbit mandibles and studied histologically.The results showed that the BG with a particle size less than 100 nm was prepared successfully.The measured BET specific surface area and pore volume was 113.9 m2/g and 0.28 cm3/g respectively.Cell cultures revealed that BG has been shown to have good biocompatibility and is also beneficial to the survival of Schwann cells,which can promote cell proliferation in vivo assay indicating that the BG can promote osteoconductivity.
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